THE STUDY OF EFFICACY OF SUBLINGUAL MISOPROSTOL IN TERMINATION OF EARLY PREGNANCY

Authors

  • Arti Kumari Senior Resident, Dept. of Obs. and Gynae., JLN medical College, Bhagalpur
  • Usha Kumari Professor and Head of Department, Dept. of Obs. and Gynae., JLN medical College, Bhagalpur
  • Anupama Sinha Associate Professor, Dept. of Obs. and Gynae., JLN medical College, Bhagalpur

DOI:

https://doi.org/10.32553/ijmbs.v5i2.1724

Abstract

Introduction: Nearly 20% of all confirmed pregnancies end in spontaneous abortion. Misoprostol’s use in early pregnancy failure is varied and dose and route are not well established. AIM: To study the efficacy of sublingual misoprostol in causing expulsion of products of conception in early pregnancy failure.

Methods: Women with an ultrasound diagnosis of early pregnancy failure, less than 12 weeks gestation were included in the study. Tablet Misoprostol 600 mcg was given six hourly sublingually for 3 doses. All observations were noted and analyzed. Results: Mean gestational age was 7.946+1.2 weeks. Mean induction abortion interval was 18.241+1.2 hours. Women with gestational age six to eight weeks had least mean induction-abortion interval time of 17.38+2.86. Mean dose required was 1560mcg. Efficacy of protocol was 92.85% in achieving complete abortion.

Conclusion: The regime had 92.85% efficacy, acceptability (90%) and few side effects. Thus by using a lower dose and appropriate interval between two doses (six hours), the side effects were lessened with high efficacy.

Keywords: Efficacy, Missed Abortion, Misoprostol.

Downloads

Published

2021-02-05

How to Cite

Kumari, A. ., Kumari, U. ., & Sinha, A. . (2021). THE STUDY OF EFFICACY OF SUBLINGUAL MISOPROSTOL IN TERMINATION OF EARLY PREGNANCY. International Journal of Medical and Biomedical Studies, 5(2). https://doi.org/10.32553/ijmbs.v5i2.1724

Issue

Section

Articles