ANEMIA IN SICKLE CELL TRAIT
Keywords:Anemia, Sickle & Trait.
Background & Method: Subjects for the study were recruited from the rural comprehensive sickle cell program at Index Medical College Hospital & Research Centre, Indore. These patients were followed up with regularly at the comprehensive sickle cell clinic with all relevant clinical and laboratory data documented in detailed case report forms. Patients were advised to follow up on a monthly basis or as symptoms presented.
Result: In our study we found, maximum no of cases in age group of 01-15 (45.6%) followed by 16-30 (30.6%)
In our study we found 11 males >18years & 19 males <18 years & 11 females >18 years & 05 females <18 years.
Conclusion: We provide for the first time detailed prevalence data of the ?s gene among Rural Population ethnic groups in Central India. These population screening programs have uncovered previously undiagnosed cases, provided detailed information for population based disease counseling, prevention programs and comprehensive care programs. Over 5,000 individuals were identified with SCT and more than 1,000 individuals were identified with SCD through community-based and target high-risk screening. The population screening study shows how community-based screening can identify individuals who may not have otherwise sought care and guide individuals to available comprehensive care centers. The screening also helped identify specific sub-groups within the Rural Population that have higher prevalence rates of the ?s gene. An estimated 1.1 million individuals in the state of Madhya Pradesh alone are expected to have SCT. Similar community-based screening programs need to be initiated throughout regions of India that have a high prevalence of Rural Population to determine the true prevalence of the ?s gene in India.
In summary, there appeared to be a broad general knowledge of sickle cell disease in the identified. target samples, with many 1nteresting comparative responses to the attitudinal survey, but no statistically significant differences 1n black and white responses in western countries.
That all persons experiencing genetic disease have the option to choose genetic counseling and sufficient community education to know they have this choice. That all genetic counseling include supportive family therapy and education over a sufficient period of time so the family can integrate the information into their own life systems.
Keywords: Anemia, Sickle & Trait.
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