TO STUDY OF PROSPECTIVE AND RETROSPECTIVE CASES OF CARCINOMA PROSTATE & HISTOLOGICAL TYPING OF CARCINOMA PROSTATE CASES

Abstract

Background & Method: The present study was carried with an aim to study of prospective and retrospective cases of carcinoma prostate & Histological typing of carcinoma prostate cases out in the Department of Pathology, Index Medical College, Hospital & Research Centre, Indore. Patients whose prostatic biopsies /TUR (Trans-urethral resection) prostate chips/ Prostatectomies were reported as carcinoma prostate. Diagnosed cases of carcinoma prostate were selected and clinical details of the patients were noted. The paraffin blocks of these cases were retrieved, for prospective cases, needle biopsies/TUR prostate chips/prostatectomy specimens received were processed, (for TUR chips the entire sample was processed) are Labelling - Histopathological section serial numbers were assigned after receiving the specimen & Tissue was fixed in 10% formalin for 12-24 hrs.

Result: Majority of cases of carcinoma prostate in our set up are diagnosed through histopathological examination of TUR prostate chips. Histopathological typing:  97 cases (97%) - Adenocarcinomas; includes 1 case of large duct carcinoma; 02 cases (02%) - Small cell carcinomas; oat cell type; 01 case   (01%)  - Adeno-squamous carcinoma

Conclusion: The histologic grade ought to be important for the clinical arranging, utilizing the degree of danger of growth to assist with picking the treatment offering the best advantage to chance proportion. Therapy determination isn't basic & has changed drastically during that time Orchiectomy & estrogen treatment overwhelmed therapy for a really long time.: Radical prostatectomy came & went alongside radiation treatment when it demonstrated hard to archive advantageous impacts, & the advantage to inconvenience proportions were less positive than they are today. As of now, revolutionary prostatectomy with the somewhat new nerve-saving activity is the inclined toward methodology on the off chance that the growth has all the earmarks of being restricted to the prostate.

Keywords: Carcinoma, Prostate & Histological.