Background: We designed a study to compare radiotherapy alone in sandwich set up with concurrent chemo radiotherapy in the management of breast cancer.
Methods: This study was conducted on 30 patients suffering from advanced breast carcinoma who visited Department of Radiotherapy and Clinical Oncology, S. N. Medical College, Agra. All these patients were referred from Department of Surgery, S.N. Medical College or from other nearby centers. Out of 30 patients 25 patients completed the treatment and were enrolled for analysis.
Results: 84.61% of patients had no evidence of disease and were alive without disease in arm A vs 100% in arm B. The overall survival at 1 year was 100% in both the arms. The disease free survival at 1 year was 84.61% in arm-A and 100% in arm-B.
Conclusion: The overall adverse effects were higher in ARM-B (concurrent arm) as compared to ARM-A but it was acceptable without any drop out during the treatment.
Keywords: Breast cancer, concurrent chemoradiotherapy, neoadjuvant therapy, locally advanced disease.