ASSOCIATION BETWEEN CHRONIC KIDNEY DISEASE AND PLASMA HOMOCYSTEINE LEVEL - A HOSPITAL BASED STUDY
Keywords:Homocysteine, GFR, CKD
Background: CKD is defined as the presence of kidney damage, manifested by abnormal albumin excretion or decreased kidney function, quantified by measured or estimated glomerular filtration rate (GFR), that persists for more than 3 months.
Methods: The hospital based cross-sectional study was conducted on 100 patients with CKD. Patients fell within the ages of 20 to 85 years and either were with stage 2–5 CKD. They were recruited from the outpatient clinic of the Division of general medicine govt. medical college, Bharatpur (Rajasthan). Patients’ diagnoses and CKD staging were confirmed by an experienced Physician.
Results: Mean value of homocysteine level was 15.35 ?mol/L in stage 2-3 and 28.34 ?mol/L in stage 4-5 of CKD patients.
Conclusion: Level of homocysteine increased according to the stages of CKD.
Keywords: Homocysteine, GFR, CKD.