International Journal of Medical and Biomedical Studies <p><strong>Aims and Scope</strong></p> <p>International Journal of Medical and Biomedical Studies&nbsp;(IJMBS) is an international, peer-reviewed, open access, online journal dedicated to the rapid publication of full-length original research papers, short communications, invited reviews, Case studies and editorial commentary and news, Opinions &amp; Perspectives and Book Reviews written at the invitation of the Editor in all areas of the Medical and Biomedical Studies.</p> <p>International Journal of Medical and Biomedical Studies&nbsp;is an academic journal which aims to publish complete and reliable source of information in the field of medical research providing the fundamental knowledge for further research.&nbsp;<em>IJMBS</em>&nbsp;commits to publish the results of researches in medical practice, risk factors and preventive medicine, safety and effectiveness of treatments, and diagnostic tools that are used to treat any disease. Our journal aims to attract an international audience of Medicine professionals enthusiastic to the most updated and substantial medical progress through the full spectrum of medical research.</p> <hr> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Medical Studies||&nbsp; Biomedical Studies ||&nbsp;</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Anatomy, Physiology, Anesthesia,<strong>&nbsp;</strong>Biochemistry, Molecular Biology, Cell biology, Genetics, Hematology, Pathology, Immunology, Microbiology, Virology, Parasitology, Surgery, Dental Sciences, Sports Physiology,&nbsp;Histopathology, Toxicology and all major disciplines of Biomedical Sciences,&nbsp;Pharmacokinetics,&nbsp;Molecular Drug Design, Phytochemistry, Toxicology, Biomedical Analysis, Clinical Research, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology,&nbsp;Agriculture, Herbal Medicine, Orthopaedics and all major disciplines of&nbsp;Medical and Biomedical Studies.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Articles are published as they are accepted and are freely available on the journal’s website to facilitate rapid and broad dissemination of research findings to a global audience.</span></span></p> <hr> <p style="text-align: justify;"><strong style="font-size: 14px; font-family: 'lucida sans unicode', 'lucida grande', sans-serif; text-align: justify;">Top Reasons for publication with us</strong></p> <hr> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Quick Quality Review:</strong> The journal has strong international team of editors and reviewers, Rapid Decision and Publication</span></span></p> <hr> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong style="font-size: 14px; font-family: 'lucida sans unicode', 'lucida grande', sans-serif;">Other features:</strong> DIDS and DOI: Assigned and Implemented the Open Review System (ORS).</span></span></p> <hr> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Important Notice:</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Author can now directly send their manuscript as an email attachment to <strong><span style="color: #008000;"></span></strong></span></span></p> <hr> <p>&nbsp;</p> IJMBS JOURNAL PUBLISHER en-US International Journal of Medical and Biomedical Studies 2589-868X <p>&nbsp;</p> <p class="caption" style="text-align: center;"><a href="" rel="license"><img style="border-width: 0;" src="" alt="Creative Commons License" width="60" height="21" border="0"></a>International Journal of Medical and Biomedical Studies&nbsp;(IJMBS)<span style="line-height: 1.3em;">&nbsp;</span><span style="line-height: 1.3em;">by </span><span style="line-height: 1.3em;">Articles</span><span style="line-height: 1.3em;"> is licensed under a </span><a style="line-height: 1.3em;" title="Journal of Biomedical and Pharmaceutical Research" href="" target="_blank" rel="license noopener">Creative Commons Attribution 4.0 International License</a><span style="line-height: 1.3em;">.</span></p> Ileo Ileo COLIC INTUSSUSCEPTION IN 1 YRS OLD CHILD: A RARE CASE REPORT <p>Intussusception is a common cause of intestinal obstruction and colicky abdominal pain in the children, particularly infants, the commonest being the ileocolic variety with colocolic variety being a very rare entity. We present a case of colocolic intussusception in a 1-year-old girl. A 1-year-old girl presented with history of colicky abdominal pain since 6 hours and non-passage of stools and flatus since 8 hours.The parents also gave history of 4 episodes of vomiting, vomitus contained food particles. Vomitus was not blood stained, foul smelling or bilious. Intraoperative findings included a polypoidal growth in the descending colon as the leading point with the formation of a colo-colic intussusception. The child was taken up for emergency laparotomy. Intraoperatively ilio-ileal intussception was noted at 2 levels with multiple enlarged mesenteric lymph nodes. The intussceptions were reduced manually. On further exploration of the distal end of bowel, appendix was found to be elongated and inflamed. Appendectomy was done, and the sample sent for histopathological examination.</p> Siddharth Kumar Sinha Dhaval Desai Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-18 2020-10-18 4 10 10.32553/ijmbs.v4i10.1469 A STUDY OF ANEMIA IN BETA – THALASSEMIA CARRIER PATIENTS IN INDEX MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTER, INDORE ( M.P.) <p><strong>Background: </strong>This study was conducted at Index Medical College, Hospital and Research Center, Indore (M.P.) from June 2019- May 2020.</p> <p><strong>Material and Methods:</strong> Patients attending the department of haematology and referred from other periphery area after written consent (below and above 18 years patients of both gender) were included in the study. There haemogram and blood group, blood urea , serum creatinine, serum iron and vitamin B – 12 level, urine R/M and stool test for worm infestation and liver function were done bedside all relevant investigations. There blood sample for electrophoresis was done HbA1 and HbA2 and HbS who had criteria that showed thalassemia with a peripheral blood picture and electrophoresis with Hb less than 10 gm/dl were noticed and analysis done .</p> <p><strong>Exclusion Criteria:</strong> Patient who had more than 10 gm haemoglobin, pregnant women, patients who refused for written consent with other haematological disorder such as sickle cell anemia, patients who had undergone blood transfusion within 4 months, patients suffering from HIV and HBV – HCV infection , patients of tropical splenomegaly and cancer patients .</p> <p><strong>Results:</strong> In females, below 18 years, total patients were 13 out of which 12 patients needed blood</p> <p>transfusion and above 18 years, total patients were 27 out of which 25 patients needed blood transfusion.</p> <p>In males, below 18 years, total patients were 22 out of which 19 patients needed blood transfusion and above 18 years, total patients were 13 out of which 9 patients needed blood transfusion.</p> <p><strong>Conclusion: </strong>Most of the carriers are asymptomatic but few of them had symptoms and may need blood transfusion also. Pre-marital counseling for genetic disorder through genetic counseling is good tool to lesson the burden of genetic transmitted disease and recurrent transfusion and iron - overloaded.</p> <p><strong>Keywords: </strong>Beta - thalassemia and its type, MCH (mean cell hemoglobin), MCV (mean corpuscular volume), MCH C (mean cell hemoglobin concentration ), Hb A1 (adult hemoglobin ), Hb A2(adult hemoglobin), HbF (fetal hemoglobin).</p> Bushra Khanam Pradeep Gupta Sumit Solanki Mohammed Imran Khan Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-17 2020-10-17 4 10 TO CORRELATE BETWEEN BIOCHEMICAL PARAMETERS AND DIFFERENT GRADES OF OBESITY <p>Background &amp; Method: In this case control (observational) study we include 114 participant (n=57 cases and n=57 controls) in this case and controls taken using standard sampling procedure participants are taken who attend Medicine OPD in Netaji Subhash Chandra Bose Medical college Jabalpur in period of March 2015 to August 2016.</p> <p>Result: We didn’t found significant difference in cases on the basis of BMI and FBS,PPBS and GTT.We found correlation in cases on the basis of BMI and in Lipid Profile and we found there is significant difference in low density lipid level in overweight and moderate obese (t&gt;2.08) and Triglyceride level and Serum cholesterol/HDL ratio in overweight and sever obese (t&gt;1.97, t&gt;2.41) and moderate and severe Obese (t&gt;2.14, t&gt;2.10).</p> <p>Conclusion: In cases on the basis of Diastolic dysfunction and Lipid Profile we found significant difference between serum cholesterol/HDL levels in those who had Diastolic dysfunction compare to who don’t have Diastolic dysfunction. Diastolic dysfunction appears not to be influenced by sex. The association between diastolic dysfunction and obesity according to sex is not significant. In cases on the basis of BMI and FBS, PPBS and GTT we don’t found significant difference in cases. In grades of Diastolic Dysfunction and Lipid profile and we doesn’t found any significant difference in grade 1 and grade 2 diastolic dysfunction on the basis of lipid profile.</p> <p>Keywords: BMI, Left Ventricular, Transthoracic &amp; Echocardiography.</p> Hemant Nargawe Devidas Shankar Bantewad Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-16 2020-10-16 4 10 10.32553/ijmbs.v4i10.1464 TO STUDY THE ETIOPATHOLOGICAL SPECTRUM OF ADULT PATIENTS WITH PANCYTOPENIA <p>Background: Pancytopenia is diagnosed when there is a reduction in all three hematopoietic cell lines. Till date there is limited number of studies on the frequency of various causes of pancytopenia. Of these some have been reported from the Indian subcontinent. There appears to be a changing spectrum of pancytopenia over the past two decades. The objective was to study the etiopathological spectrum of adult patients with pancytopenia over a period of one and half year.</p> <p>Methods: The Prospective and retrospective observational study was conducted in the Department of Family Medicine, Batra Hospital and Medical Research Centre, New Delhi.&nbsp; A total of 120 Patients were included in the study. All patients gave their consent to take part in the study and were subjected to a questionnaire regarding symptoms, past relevant history, lifestyle and detailed clinical examination and investigations as mentioned in materials and methods.</p> <p>Results: Six broad diagnostic groups could be identified in adults with pancytopenia. Megaloblastic anemia (D1) was the largest group comprising 57.5% of all patients. 11.7% of patients with pancytopenia were diagnosed as Aplastic anemia (D2).11.7% of patients with pancytopenia were diagnosed as leukemia/lymphoma (D3) such as lymphoma (1), metastatic anaplastic carcinoma (1), acute leukemia (11), and metastatic gastric carcinoma (1). 15% of patients with pancytopenia were diagnosed with infections (D4) such as complicated malaria cases (7), HIV (5), disseminated tuberculosis (4), viral (2). We also encountered (D5) 0.8% was Myelophthisis/Storage disorder as myelodysplastic syndrome (1) and 3.3% were other (D6) as reactive marrow (4).</p> <p>Conclusion: Pancytopenia is not a disease itself. It is a hematological feature of varying etiology with slight male preponderance. Megaloblastic anemia along with mixed nutritional anemia is leading cause of pancytopenia in India followed by infections being second and aplastic anemia and acute leukemia being third common causes.</p> <p><strong>Keyword:</strong> Pancytopenia, Megaloblastic anemia, Nutritional anemia.</p> Harimohan Garg Haritej Anand Khirawari Sona Priyadarshi Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-15 2020-10-15 4 10 10.32553/ijmbs.v4i10.1461 A STUDY TO COMPARE THE EFFICACY OF THREE SUTURING TECHNIQUES IN REDUCING THE DEVELOPMENT OF POST-OPERATIVE COMPLICATIONS AMONG PATIENTS WITH GENERALIZED PERITONITIS WHO UNDERWENT EMERGENCY MIDLINE LAPAROTOMY WHILE ADMITTED IN THE GENERAL SURGICAL UNITS OF <p>Background: This study seeks to allocate patients into two groups: one, in which the continuous technique is used for the closure of the linea alba, and the other in which an interrupted technique is used. The study aspires to observe and record wound complications after midline laparotomy incisions in the hope of spurring renewed interest in abdominal closure, and possibly gathering evidence that warrants change in the current trend, or evidence encouraging the ongoing practice.</p> <p>Methods: A descriptive design was used to conduct the study. The purpose of the design was to compare and document the post-operative complications arising with the use of three suturing techniques. The suture technique was based on the discretion of the operating surgeon. It was a prospective randomized study where all consecutive subjects who fulfilled the inclusion criteria were incorporated. The study comprised of 100 subjects.</p> <p>Results: There was a male predominance in the subject profile. Males comprised 79% of the study population. Peptic perforation was the most common cause of generalized peritonitis in the population under study. Patients with interrupted closure had a lower incidence of wound infection, wound dehiscence, burst abdomen, and incision hernia as compared to those closed by the continuous technique. The difference was not statistically significant. Jaundice, renal failure, enteric fever, and presence of stoma were associated with an increased risk of wound disruption. Pulmonary disease was associated with increased post-operative wound dehiscence, burst abdomen, and development of incisional hernia. Admission to the surgical intensive care unit and mechanical ventilation are associated with an increased risk of development of post-operative wound disruption and subsequent incisional hernia. As it was found that 40% of subjects who developed incisional hernia had a preceding wound infection, the incidence of incisional hernia would be reduced by the elimination of wound sepsis.</p> <p>Conclusion: This study shows that the interrupted technique ((prof. hughes&gt; Interrupted Double-X) of fascial closure is superior to the continuous technique in prevention of both early and late wound complications in a contaminated wound. Further larger studies are indicated to demonstrate statistical significance. Various modifiable risk factors have been described to decrease the rate of development of post- operative wound complications.</p> <p><strong>Keywords:</strong> Operative, Patients, Laparotomy</p> Ravindra Palsaniya Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-18 2020-10-18 4 10 TO FIND OUT ELECTRO-CARDIOGRAPHIC CHANGES & ECHO CHANGES IN ALUMINIUM PHOSPHIDE AND ETHYLENE DIBROMIDE POISONING <p>Background &amp; Method: The study was conducted in the Department of Medicine Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa (M.P). History was followed by a careful clinical examination i.e. cardiovascular, respiratory and gastrointestinal and nervous system. Investigations had done included routine haematological examination, Biochemical analysis, urine examination, ECG, 2 D. Echo &amp; Histopathological examination was done.</p> <p>Result: ST-T changes were most common finding in Aluminium phosphide poisoning in relation to mortality. However hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG. The most ominous finding was arrhythmia which was associated with 100% mortality. Survivors of ethylene dibromide poisoning echocardiography was normal in 11 (84.61%) followed by pericardial effusion in 2 (15.38%) patients.</p> <p>Conclusion: Noteworthy finding was absence of correlation between cardiovascular involvement, histopathological changes and ECG findings. It was seen that even if ECG showed normal pattern there were significant histopathological changes in heart.</p> <p><strong>Keywords:</strong> electro-cardiographic, Aluminium phosphide, ethylene dibromide &amp; poisoning.</p> Hemant Nargawe Sumeet Sisodiya Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-16 2020-10-16 4 10 10.32553/ijmbs.v4i10.1465 KNOWLEDGE AND ATTITUDE OF DENTAL SURGEONS ABOUT USE OF DENTURE ADHESIVE. A QUESTIONNAIRE BASED STUDY. <p>Aims and Objectives: The basic purpose of this study is to evaluate the knowledge and attitude of general dental surgeons (Dentist) toward use of denture adhesive in complete denture.</p> <p>Materials and Methods; A detailed questionnaire was prepared and a total of 100 dentist were surveyed using this questionnaire, in order to understand the knowledge and attitude about denture adhesive in complete denture.</p> <p>Result; The result of this survey shows that about 56% of dentist know about denture adhesive, and 56.6% reported improved mastication retention and stability. Most the dentist is well aware about denture adhesives in Darbhanga town but their knowledge is only limited to the use of denture adhesives.</p> <p>Conclusion; the knowledge of denture adhesive among dentist in Darbhanga town is not as much as expected, however they are using it in their clinical practice since long.</p> Ahtasham Anwar Shagufta Syreen Bimleshwar Kumar Jay Parkash Narayan Nisha Kumari Copyright (c) 2020 International Journal of Medical and Biomedical Studies 2020-10-15 2020-10-15 4 10 10.32553/ijmbs.v4i10.1462 TO ASSESS THE ROLE OF DWI IN CHARACTERIZING THE RENAL NEOPLAMS INTO THE VARIOUS SUBTYPES USING THE ADC VALUES OF THE LESIONS AND FINDING ITS ACCURACY BY HISTOPATHOLOGICAL CORRELATION. <p>This prospective study was done in the Department of Radiodiagnosis at M.G.M. Medical College, &amp; M.Y. Hospital, Indore. A total of 40 patients who were referred to our department with strong clinical suspicion of renal lesion and those diagnosed by ultrasonography or contrast enhanced CT scan having a renal mass on either of them, were subjected to a non-contrast.</p> <p>ADC values are expressed in 10<sup>-3</sup> mm<sup>2</sup>/s.&nbsp;DW imaging with ADC values allows differentiation of clear cell, papillary and chromophobe subtypes of RCCs, suggesting that DW imaging may be a useful tool in the preoperative characterization of RCC. Hence, MRI with DWI in particular is a very valuable non invasive tool for the Identification, characterization and differentiation of renal lesions.</p> <p>Study Designed: Observational Study.</p> <p><strong>Keywords:</strong> DWI, Renal, Neoplams, ADC, Histopathological &amp; Correlation.</p> Nitin Kumar Tripathi Sanjay Kumar Tekam Copyright (c) 2020-10-08 2020-10-08 4 10 10.32553/ijmbs.v4i10.1451 HYDATIDIFORM MOLE: A REVIEW OF MANAGEMENT OUTCOMES IN A TERTIARY HOSPITAL, SIR T HOSPITAL, BHAVNAGAR <p>Hydatidiform mole is the non- malignant form of gestational trophoblastic neoplasia. The prevalence of 1:250 to 1:500 has been reported which vary widely in different parts of the world. Therefore, Knowledge of prevalence and associated risk factors may add value in the management outcomes of molar pregnancy in our setting. 20 women who clinically diagnosed with hydatidiform mole<a href=";enrichSource=Y292ZXJQYWdlOzI0MTI3NzMzNztBUzo5NzEyOTQ1MjI3Nzc3MUAxNDAwMTY4ODc0OTY5&amp;el=1_x_3&amp;_esc=publicationCoverPdf">&nbsp; in Tertiary</a> Hospital, Sir T Hospital, Bhavnagar were included in study. The diagnosis of HM was based on a pelvic ultrasonography, quantitative estimation of the serum beta human chorionic gonadotrophin (B-hCG) and confirmed by histopathologic specimen taken during suction evacuation. 60% patients were of age between 20-25 years, 60% patients had gestational period between 1-2 months. All 20 patients had bleeding PV. 1 patient developed PIH. 2 patients had ovarian enlargement. 1 patient had invasive mole. No patient had choriocarcinoma. 55% patient developed hyperthyroidism. 1 patient had complication of pulmonary embolism. All 20 patients were treated by uterine suction and evacuation. The use of Ultrasonography in the evaluation of vaginal bleeding in early pregnancy, as well as histologic evaluation of products of conception,&nbsp; is important in early diagnosis and treatment H- mole. There is need for early recognition, timely referral, prompt and proper treatment of this condition.</p> <p><strong>Keywords: </strong>Hydatidiform mole , suction evacuation , human chorionic gonadotrophin (B-hCG)</p> Vasava Amarpali Puransinh Kanaklata D. Nakum Aditi Vithal Copyright (c) 2020-10-10 2020-10-10 4 10 10.32553/ijmbs.v4i10.1453 TO EVALUATE EFFECT OF HORIZONTAL HIP OFFSET AND LEG LENGTH RECONSTRUCTION ON FUNCTIONAL OUTCOME OF TOTAL HIP REPLACEMENT <h3>Background: For total hip replacement besides long term durability a optimal postoperative functional outcome is aim of this study was to determine the combined influence of hip geometry reconstruction on the clinical outcome following primary total hip replacement for unilateral osteoarthritis.</h3> <p>Methods: A hospital based prospective study was carried out on 60 cases of unilateral osteoarthritis with normal contralateral hip. We prospectively assessed the clinical outcome and radiographic parameters for hip geometry reconstruction using validated measurements for the operated hip compared to the contralateral native hip with primary unilateral THA. The correlation of reconstruction parameters was investigated using a multivariate polynomial regression model for the dependent variable ?HHS (difference between the Harris hip scores preoperatively and 6 months postoperatively). Target zones for hip reconstruction were investigated for an association with superior clinical outcome.</p> <p>Results: The regression model demonstrated a significant correlation for the ?HHS and both hip offset (HO) reconstruction and leg length difference. Patients with accurate to slightly increased HO reconstruction combined with balanced leg length demonstrated a significantly higher ?HHS than patients outside this zone.</p> <p>Conclusion: HO and leg length reconstruction demonstrated an additive effect on clinical outcome and surgeons should aim for high accuracy in the reconstruction of both factor.</p> <p><strong>Keyword: </strong>Hip offset, total hip arthoplasty, harris hip score</p> Harshit Jain Hemraj Saini Copyright (c) 2020-10-12 2020-10-12 4 10 10.32553/ijmbs.v4i10.1455 TO DETERMINE THE SERUM PROLACTIN LEVELS IN BREAST CARCINOMA: A CASE CONTROL STUDY <p>Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers with an estimated 1.67 million new cancer cases diagnosed in 2012.</p> <p>Methods: The study was conducted in the Department of General Surgery, SMS Hospital, Jaipur. Study duration: From March 2018 to February 2019 (1 year).</p> <p>Results: In Cancer cases, Mean Serum Prolactin level was found to be 14.71±16.73 while in control it was 8.26±5.60 .Mean Serum insulin level was higher in Cancer cases (14.71) as compared to control (8.26).Range of prolactin level in breast cancer cases from 2.84 to 103.71 and Range of prolactin level in controls was from 2.79 to 33.12 Difference was found to significant.</p> <p>Conclusion: By this study we can interpretate that serum prolactin level is an independent factor and can be used to know the risk of breast cancer in postmenopausl women. whenever serum prolactin level is raised in these women, we can advise necessary measure to these women to prevent or identify early breast cancer.</p> <p><strong>Keywords:</strong> Breast, cancer, Female</p> Sahun . Sumita A. Jain Ashutosh . Dikhsa Mehta Copyright (c) 2020-10-14 2020-10-14 4 10 10.32553/ijmbs.v4i10.1456 THE EFFICACY OF HIGH CONDYLECTOMY IN INTERNAL DERANGMENT OF THE TEMPOROMANDIBULAR JOINT <p>Background: Temporomandibular joint (TMJ) is a giglymoarthroidal Joint; it is the only mobile joint in the entire maxillofacial region and is a part of craniomandibular articulation.</p> <p>Methods: All the patients with internal derangement of temporomandibular joint having&nbsp; anterior disc displacement without reduction with complaints of pain and limited opening of mouth, of all age group&nbsp; reporting to the Department of Oral &amp; Maxillofacial Surgery, GDC Jaipur were included in the study.</p> <p>Results: At one month follow up out of 20 patients 13 patients were not satisfied and at 6 month follow up 2 patients were not satisfied at all.</p> <p>Conclusion: We conclude that surgical treatment for internal derangement of the TMJ is required; this technique is effective to improve pain and mouth opening without complications. Although this study has a short follow up period and small sample size.</p> <p><strong>Keywords:</strong> Mandible, Maxilla, TMJ.</p> Vikas Sarowa Vishnu Dayal Vyas D.K. Gupta Anjali Dave Tiwari Copyright (c) 2020-10-14 2020-10-14 4 10 10.32553/ijmbs.v4i10.1457 A STUDY TO ASSESS PREDICTIVE ROLE OF C-REACTIVE PROTEIN IN EARLY PREGNANCY AMONG WOMEN <p>Background: High concentrations of maternal C-reactive protein have been associated with adverse pregnancy outcome, and premature uterine contraction may be predicted by elevated levels of C-reactive protein.</p> <p>Methods: Hospital based comparative analysis was conducted on women with early pregnancy upto 14 weeks with either abdominal pain or vaginal bleeding or suspected extrauterine pregnancy. C-reactive protein (CRP) quantitative estimation is done by turbi-diametric method.</p> <p>Results: The mean c-reactive protein level in cases 2.23 with min-max value ranging from 0.82-3.94 mg/dl while in controls mean c-reactive protein value came to be 9.15 with min-max range from 3.11-24.9mg/dl.</p> <p>Conclusion: Our results of significantly increased CRP levels in normal pregnancy and a clear association between CRP and normal pregnancy, support the clinical application of this diagnostic tool in early pregnancy, especially as a predictor of abnormal first trimester pregnancies.</p> <p><strong>Keywords:</strong> Diagnostic, CRP, Pregnancy, Women.</p> Asmita Nayak Ruchi Saxena Gajendra Saxena Copyright (c) 2020-10-14 2020-10-14 4 10 10.32553/ijmbs.v4i10.1458 JOINT WORKING IN A FRAGMENTED SYSTEM: CHALLENGES IN MATERNAL AND CHILD CARE PROVISION IN THE CORONAVIRUS PANDEMIC <p><span class="TextRun SCXW115485600 BCX0" lang="EN-US" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW115485600 BCX0">In policy documents worldwide, the issue of maternal and child mortality and morbidity is identified as an urgent health concern [SDGs, 2016]. The Integrated Child Delivery Service [ICDS] and National Health Mission [NHM] jointly attempt to address the issue of maternal and child health in India. On the ground, these programs are operationalized by the frontline workers of the two programs – the Accredited Social Health Activists [ASHAs], the Auxiliary Nursing Midwives [ANMs] and the Anganwadi Workers [AWWs]. The purpose of designing joint activities between the two programs is to integrate both the social and the medical aspects of health [Sharma, 2014]. However, while the two programs are designed to be compatible, coordination issues exist in their joint implementation [Kim et al., 2017; Prasad et al., 2012].&nbsp; Currently, because of the allocation of additional responsibilities for the frontline workers, challenges for frontline workers have exacerbated [Indian Express, 2020]. In real terms, the increased problems in coordination in integrated care provision could potentially result in increased incidents of morbidity and mortality for this demographic. In this context, this article discusses and anticipates challenges for the frontline workers for providing maternal and child health in India.</span></span><span class="EOP SCXW115485600 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:480}">&nbsp;</span></p> Arnav Mahurkar Copyright (c) 2020-10-14 2020-10-14 4 10 10.32553/ijmbs.v4i10.1452