International Journal of Medical and Biomedical Studies

Artificial Intelligence-Based Semantic Internet of Things

Rashid Ayub, Prasadu Peddi — Tue, 05 Sep 2023 00:00:00 -0400

As more and more smart devices are connected to the internet, IOT technologies are enabling new uses in the SC that go beyond the SH. The people of a smart city (SC) may get the help they need thanks to SC technology. Connectivity between vast arrays of devices is made possible by IOT technology, making it a crucial enabler in a SC. Despite the fact that modeling the side-effects of sensing based on resource state is difficult and selecting the wrong actions could exacerbate the effect, AI-based Semantic Internet of Things (such as our Observer Effect MDP) approaches that take resource state into account will outperform those that do not.

Keywords: resource, Markov decision process, Internet of Things, Artificial Intelligence

Formulation of Metoprolol Tartarate Containing Lyophilized Oral Disintegrating Tablet

Shashank Gupta, Sachin Kumar Jain , Sudha Vengurlekar — Thu, 28 Sep 2023 00:00:00 -0400

Orally Disintegration Tablet (ODTs) are solid dosage forms containing active pharmaceutical ingredient (API) which disintegrate rapidly, usually less than 60 seconds without the need of water when placed on the tongue. Metoprolol, which is practically water insoluble, shows low bioavailability.

weighed 100mg metaprolol was dissolved in 100ml of methanol solution to get a solution containing 100mcg/ml.

Dilution: Aliquots of (0.1-1.0ml) standard solution were pipette out into 10ml volumetric flasks. The volume was made upto the mark with methanol solution to produce the concentration ranging from 1-10 mg/ml. The absorbance of each prepared solution was measured at 222nm in Shimadzu UV-1800 spectrophotometer against an appropriate blank (Methanol solution).

Lyophilization is one of the technique that can solve this problem in ODTs formulation.

The resulting tablets were evaluated using parameters such as: hardness, friability, disintegration time in vitro, modified disintegration time, disintegration time in the oral cavity, wetting time, water absorption ratio, drug content determination, weight uniformity, and dissolution.

Keyword: ODTs ( Oral disintegrating tablet), Lyophilized, Formulation, Metoprolol Tartarate, Disinteration, Gelatin

Peripheral Ossifying Fibroma in A Pregnant Female – A Case Report

Jaspreet Kaur, Baljeet Singh, Akshita Singh Thakur, Tanvi Ohri — Wed, 27 Sep 2023 00:00:00 -0400

The gingiva is often the site of localized growths that are considered to be reactive rather than neoplastic in nature. Many of these lesions are difficult to be identified clinically and can be identified as specific entity only on the basis of typical and consistent histomorphology. Peripheral ossifying fibroma (POF) is one of the inflammatory reactive hyperplasia of gingiva. It is a non-neoplastic entity, which occurs on the gingiva in response to trauma or irritation. A clinical report of a 26-year-old pregnant female with a large peripheral ossifying fibroma in the anterior maxilla showing significant growth is presented.

Keywords: Ossifying fibroma, pyogenic granuloma, trimester, osteogenesis, exostoses.