International Journal of Medical and Biomedical Studies

Association of Serum Vitamin D Levels in Patients with Allergic Rhinitis at a Tertiary Care Health Centre in Bihar

Rajeev Kumar, Rajeev Ranjan, Pawan Pratap Singh, Kumar Pranay, Dilip Kumar — Wed, 24 Sep 2025 00:00:00 +0000

Background: Allergic rhinitis (AR) is a chronic inflammatory nasal disorder mediated by IgE and is becoming increasingly common worldwide. Apart from its role in calcium metabolism, vitamin D has regulatory functions in immunity that may influence AR severity.

Objective: To evaluate the relationship between an individual's severity of allergic rhinitis and their serum vitamin D levels.

Methods: A retrospective cross-sectional study was conducted over the course of year the IGIMS, Patna. A total of 156 patients with clinically diagnosed AR were included after informed consent. Serum 25-hydroxyvitamin D was estimated using the Architect Abbott i2000 CMIA system. Patients with comorbidities or taking drugs affecting vitamin D were excluded. GraphPad Prism 8.0 was used for statistical analysis.

Results: Most AR patients were vitamin D deficient (<20 ng/mL). Those with deficiency had a significantly higher prevalence of moderate-to-severe persistent AR compared to individuals with sufficient levels (>30 ng/mL). An inverse correlation between vitamin D concentration and AR severity was observed (p<0.05).

Conclusion: Vitamin D deficiency is widespread among allergic rhinitis patients in Bihar and is strongly linked with more severe disease. Incorporating vitamin D screening and correction into routine management may help improve clinical outcomes

An Overview of contrast Induce Acute kidney injury

R.K Jha — Mon, 29 Sep 2025 00:00:00 +0000

The risk of contrast induced Acute kidney injury (CI-AKI) is high in CKD & diabetic patient as compared to general population. It is the third most cause of Hospital acquired AKI. Pathogenesis is not clear but there is role of direct & indirect cytotoxicity of contrast media, oxidative stress & as well as of micro-RNA. There is no specific therapy of CI-AKI, hence prevention is the cornerstone of management. Except hydration therapy all other pharmacotherapy has been failed to prove beneficial effect in preventing CI-AKI in many RCT & meta-analyses.

Keywords: contrast induced acute kidney injury (CI-AKI), pathogenesis, contrast media

Prevalence of altered vibration perception and Orthostatic Hypotension in Type II Diabetes Mellitus: A Cross Sectional Study in a manufacturing unit

Wed, 08 Oct 2025 00:00:00 +0000

Background: Type 2 Diabetes Mellitus (T2DM) is associated with a variety of vascular complications, including Diabetic Peripheral Neuropathy (DPN), which affects over 40% of patients within 10 years of diagnosis. Undiagnosed DPN can significantly diminish quality of life and increase mortality. For early prognosis, plantar Vibration Perception Threshold is considered an important indicator for Diabetic Peripheral Neuropathy