CORRELATING BIOCHEMICAL, RADIOLOGICAL AND CYTOLOGICAL OUTCOMES OF PLEURAL EFFUSION

Abstract

Introduction: The research emphasises on the association bond of correlation of biochemical radiological and cytological outcomes of pleural effusion

Material and Methods: The samples for the study were collected from the diagnostic centre, out-patient department and in-patient department of Department of Biochemistry, Internal Medicine, Respiratory Medicine at Rabindranath Tagore Medical College, Udaipur, Rajasthan The research was carried out on a total of 100 patients .The observations took about a year’s time. The research was carried out on a total of 100 patients,

Results: 100 patients with pleural effusion were studied of which 60.00% were cases of tuberculous effusion and 40.00% were cases of non tuberculous effusion. This was reflective of the high prevalence of tuberculosis in the area being studied. The remaining 40 cases were of malignant effusion (15 cases), Transudative effusion (13 cases), synpneumonic effusion (8 cases) and 4 cases of empyema.. In patients of age more than 40 years, malignant effusion was more common; It was found more common in lower socioeconomic class such people live in crowded, unhygienic conditions. The commonest symptoms were cough (81.32%) and breathlessness (78.76%), followed by fever 69.20%, weight loss 64.64%, chest pain 45.50%, loss of appetite 63.30% and hemoptysis 15.80%.

Conclusion: Thus it can be concluded that ADA is elevated in tubercular pleural effusion. Exudatives had decreased glucose but increased protein, LDH and cholesterol compared to transudatives Pleural fluid cytology revealed elevated Lymphocytes in tubercular and polymorphs in acute infections

Keywords: Lactate dehydrogenase, Adenosine Deaminase biochemical, radiological and cytological  outcomes of pleural  effusion