PROSPECTIVE STUDY TO ANALYZE CALCIUM CREATININE RATIO IN A SPOT SAMPLE OF URINE FOR EARLY PREDICTION OF HYPERTENSIVE DISORDER IN PREGNANCY

Authors

  • Kuntal B Prajapati Department of Obstetrics and Gynecology, Sir Takhatsinhji, Government Medical College, Bhavnagar, Gujarat.
  • Kanaklata D. Nakum Department of Obstetrics and Gynecology, Sir Takhatsinhji, Government Medical College, Bhavnagar, Gujarat.

DOI:

https://doi.org/10.32553/ijmbs.v4i3.1027

Keywords:

Calcium creatinine ratio, Gestational hypertension, Preeclampsia, Preeclampsia prediction

Abstract

Hypertension in pregnancy is a big threat to the mother as well as the fetus. Predi³³ction of preeclampsia with reasonable accuracy is one of the essential prerequisites for its prevention. Various biological markers are available for the prediction of preeclampsia but none of those is reasonably reliable, valid and economical. In this present study, the predictive value of the urinary calcium-creatinine ratio (CCR) for the prediction of preeclampsia was studied. This study was conducted at department of Obstetrics and Gynaecology, Sir T Hospital, Government Medical college, Bhavnagar. 500 Primigravida patients attending the antenatal outpatient department at Sir T Hospital between 18 to 24 weeks of gestation were registered in this study.  Single voided urine sample was collected from all the patients in calcium free vial for estimation of urine calcium and creatinine. After initial workup, all patients were followed in the antenatal clinic till the time of delivery and 15 days post partum. The number of patients who develop the hypertensive disorder in pregnancy was noted and the correlation studied. Out of 500 patients, 120 patients (24%)developed preeclampsia,4 patients(0.8%)developed eclampsia,10 patients (2%) developed gestational hypertension. Out of 500 patients, 84 patients (16.8%) showed UCCR<0.04.The remaining 416 patients (83.2%) showed UCCR>0.04. Out of 84 patients with UCCR<0.04, 2 patients (2.38%) developed Gestational Hypertension. : A single estimation of calcium to creatinine ratio in asymptomatic pregnant women between 18-24 week of gestation is a simple and cost-effective test. A value of less than or equal to 0.04, in a spot urine sample, has a good predictive value for preeclampsia

Keywords: Calcium creatinine ratio, Gestational hypertension, Preeclampsia, Preeclampsia prediction

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Published

2020-03-11

How to Cite

Prajapati, K. . B., & Nakum, K. D. (2020). PROSPECTIVE STUDY TO ANALYZE CALCIUM CREATININE RATIO IN A SPOT SAMPLE OF URINE FOR EARLY PREDICTION OF HYPERTENSIVE DISORDER IN PREGNANCY. International Journal of Medical and Biomedical Studies, 4(3). https://doi.org/10.32553/ijmbs.v4i3.1027

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Section

Research Articles