ASSESSMENT OF BLOOD GLUCOSE LEVELS AND SEVOFLURANE REQUIREMENT IN PATIENTS ON DEXMEDETOMIDINE INFUSION FOR INTRA-PERITONEAL SURGERIES
The aim of the present study was to observe the effect of intravenous Dexmedetomidine on levels of blood glucose, which is one among several stress response markers under General Anesthesia (GA) for laparoscopic intra-peritoneal surgeries.
The study was planned in the Department of Anaesthesia in Sri Krishna Medical College and Hospital, Muzaffarpur, from Jan 2016 to Oct 2016.The 30 patients undergoing for laparoscopic intra-peritoneal surgeries of 1-2 hours duration with minimal expected blood loss were enrolled. The approval of the institutional committee was taken prior conduct of study. All the patients were informed consents. The 15 patients in Group A received loading dose of Inj. Dexmedetomidine 1µg/kg/10min diluted to 50ml with Normal Saline, given before induction, followed by maintenance dose 0.5µ/kg/hour till the end of surgery. The 15 patients in Group B received Normal Saline in a similar manner.
Dexmedetomidine, a highly selective ?2-adrenergic receptor agonist has generated lot of interest for its sedative, analgesic, perioperative sympatholytic, anesthetic-sparing, and hemodynamic-stabilizing properties. The data generated in the two study groups in the present study concludes that the use of dexmedetomidine maintains blood glucose levels and favourably influencing the intra operative stress induced blood glucose levels.
Keywords: Dexmedetomidine, Stress induced blood glucose levels, laparoscopic intra-peritoneal surgeries, etc.