THYROID DISORDERS AND POLYCYSTIC OVARY SYNDROME Dr. B S Meena1, Dr. Neeta Meena2
Background: Polycystic ovarian syndrome (PCOS) is the most common form of chronic anovulation associated with androgen excess; perhaps occurring in 5-10% of reproductive women.
Methods: Observational study done in the Department of Obstetrics & Gynaecology, SMS Medical College, Jaipur. Forty cases of women with PCOS based on Rotterdam’s criteria and an equal number of age-matched controls (women without PCOS) were included in the study.
Results: T4 level was significantly lower in PCOS group with mean free T4 level 0.87 ± 0.75 ng/ml in PCOS group v/s 1.92 ± 0.84 ng/ml in control group (p-value = 0.001). TSH level was significantly higher in PCOS group with mean TSH level 8.86 ± 7.57 mU/L in PCOS group v/s 3.40 ± 1.21 mU/L in control group (p-value = 0.001)
Conclusion: High prevalence of thyroid disorders in PCOS patients thus points towards the importance of early correction of hypothyroidism in the management of infertility associated with PCOS.
Keywords: T4, T3, TSH, PCOS