TO EVALUATE ROLE OF STRAIN ELASTOGRAPHY IN DIFFERENTIAL DIAGNOSIS OF SOLID BREAST LESIONS WITH HISTOPATHOLOGY AS GOLD STANDARD
Keywords:Elastography, MRI, USG
Background: Elastography has increased the specificity of USG and enabled early diagnosis of breast cancer. Quantitative elastography, especially with strain ratio (SR) index, improves diagnostic accuracy and decreased number of biopsies.
Aims: The purpose of this study was to assess the role of USG elastography in the differential diagnosis of solid breast lesions.
Materials and Methods: Fifty patients diagnosed with breast lesions between May 2019 and may 2020 were included in this prospective study. All the patients were examined in the supine position, compression was applied with the probe over the lesion and elastographic images were examined. The elasticity region of interest (ROI) was placed to cover the lesion and the target lesion was placed in the center and the B-mode USG image was displayed along side the elastography strain image. Elastography images were obtained by a EUS Hitachi ultrasound system with a 6.5-MHz linear probe. The elastography strain images were scored according to the Tsukuba elasticity score.
Results: In this study we included 50 patients with breast lesions confirmed on US. The average age of the women was 43.3 years. There were 23 (46%) benign and 37 (54%) malignant lesions. Among the benign nodules the common lesions were fibroadenoma. Among the malignant nodules, the most common lesion was infiltrative ductal carcinoma. To calculate the sensitivity and specificity of strain elastography, lesions with elasticity scores 1-3 were classified as benign, while those with scores of 4 or 5 were classified as malignant. Sensitivity of 85.67% and a specificity of 92.6% was obtained for Tsukuba elasticity score.
Conclusions: Elastography is a fast, simple method that can complement conventional USG examination. This method has the lowest cost/efficiency ratio and it is also the most noninvasive and accessible imaging method, with an accuracy comparable to MRI.
Keywords: Elastography, MRI, USG
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