A COMPARATIVE STUDY OF INTRATHECAL BUPIVACAINEHEAVY (0.5%) WITH BUPIVACAINE HEAVY (0.5%) PLUS DEXMEDETOMIDINE FOR LOWER ABDOMINAL SURGERIES

Authors

  • Kumar Shailesh Senior Resident, Dept. of Anaesthesiology, JLN medical College, Bhagalpur
  • Jitendra Prasad Singh Assistant Professor, Dept. of Anaesthesiology , JLN Medical College, Bhagalpur
  • Arjun Prasad Associate Professor and Head, Dept. of Anaesthesiology, JLN Medical College, Bhagalpur
  • Veena Horo Associate Professor, Dept. of Anaesthesiology, JLN Medical College, Bhagalpur

DOI:

https://doi.org/10.32553/ijmbs.v5i2.1723

Keywords:

Bupivacaine; Dexmedetomidine; intrathecal.

Abstract

Introduction: Several adjuncts like adrenaline, opioids and alpha-2 adrenergic agonists are being used with local anaesthetics intrathecally for prolongation of intra-operative and post-operative analgesia and to reduce the side-effects of high doses of local anaesthetics.

Aim: The present study was done to evaluate the onset and duration of sensory and motor block, hemodynamic effects, post-operative analgesia and adverse effects of Dexmedetomidine given intrathecally with hyperbaric 0.5% Bupivacaine.

Materials and methods: Sixty inpatients of ASA class I and II scheduled for various lower abdominal surgeries under Sub-Arachnoid Block were randomly divided into two groups of 30 each namely C (Control), D(Dexmedetomidine) . All received 12.5mg hyperbaric bupivacaine plus 0.5 ml Normal Saline in Group C (Control),10µg Dexmedetomidine (diluted in preservative free Normal saline of 0.5ml) in Group D(Dexmedetomidine) . The onset time to reach peak sensory and motor level, the regression time for sensory and motor block, hemodynamic changes and side-effects were noted.

Results: The duration of sensory and motor block, rescue analgesia was significantly prolonged in Dexmedetomidine group when compared to that of Control group.

Conclusion: Dexmedetomidine 10 µg seems to be a better neuraxial adjuvant to hyperbaric Bupivacaine.

Keywords: Bupivacaine; Dexmedetomidine; intrathecal.

Downloads

Published

2021-02-05

How to Cite

Shailesh, K. ., Singh, J. P. ., Prasad, A. ., & Horo, V. . (2021). A COMPARATIVE STUDY OF INTRATHECAL BUPIVACAINEHEAVY (0.5%) WITH BUPIVACAINE HEAVY (0.5%) PLUS DEXMEDETOMIDINE FOR LOWER ABDOMINAL SURGERIES. International Journal of Medical and Biomedical Studies, 5(2). https://doi.org/10.32553/ijmbs.v5i2.1723

Issue

Section

Articles