LDH LEVEL IN ACUTE ORGANOPHOSPHORUS POISONING AND ITS RELATION WITH SEVERITY AND MORTALITY: A TERTIARY CARE HOSPITAL EXPERIENCE

Authors

  • Suresh Kumar Nagar Department of General Medicine, J L N Medical College and Hospital, Ajmer (Rajasthan)
  • Maniram Kumhar Department of General Medicine, J L N Medical College and Hospital, Ajmer (Rajasthan)
  • V. B. Singh Department of General Medicine, J L N Medical College and Hospital, Ajmer (Rajasthan)
  • Mayank Srivastav Department of General Medicine, J L N Medical College and Hospital, Ajmer (Rajasthan)

DOI:

https://doi.org/10.32553/ijmbs.v5i4.1854

Keywords:

LDH, OP poisoning, Severity

Abstract

Background: Organophosphorus compounds have been widely used for a few decades in agriculture for crop protection and pest control. In India Organophosphorus poisoning is the most common. The objective of our study was to measure the  LDH Level in acute organophosphorus poisoning

Methods: This study was conducted among minimum 100 patients acute organophosphorus poisoning admitted in Casualty ward, MICU and attending medical ward of JLN hospital, Ajmer during Aug 2018 to July 2020. Serum lactate dehydrogenase estimation by spectrophotometric analysis using Beckman Coalter AU 680

Results: These were significantly higher among deaths on day 1 and 3(810±372.99 and 1027.09±458.26, respectively) in comparison to survivors on day 1 and 3 (538.18±300.42 and 365.19±175.49, respectively). Significant difference was found between mean values of different levels of severity of LDH on day 1 and 3.

Conclusion: In conclusion, this study found that Serum LDH can be used as biomarker in diagnosis or stratifying severity of acute OP poisoning, as it is cheap and easily available, especially in developing countries. Serial measurements of serum LDH levels in acute OP poisoning can predict the prognosis.

Keywords: LDH, OP poisoning, Severity

Downloads

Published

2021-04-05

How to Cite

Nagar, S. K. ., Kumhar, M. ., Singh, V. B. ., & Srivastav, M. . (2021). LDH LEVEL IN ACUTE ORGANOPHOSPHORUS POISONING AND ITS RELATION WITH SEVERITY AND MORTALITY: A TERTIARY CARE HOSPITAL EXPERIENCE. International Journal of Medical and Biomedical Studies, 5(4). https://doi.org/10.32553/ijmbs.v5i4.1854

Issue

Section

Articles