COMPARISON BETWEEN SERUM CREATININE AND SERUM CYSTATIN C LEVEL IN DIAGNOSING EARLY DIABETIC NEPHROPATHY IN NEWLY DIAGNOSED TYPE 2 DIABETES MELLITUS
Keywords:Cystatin C, Diabetic Nephropathies, Albuminuria
Background: This study was done to evaluate clinical usefulness of cystatin C levels of serum and urine in predicting renal impairment in normoalbuminuric patients with type 2 diabetes and to evaluate the association between albuminuria and serum/urine cystatin C. Cockroft-Gault equation was previously used for GFR calculation. The most recently advocated formula for calculating the GFR are The modification of diet in renal disease study group ,CKD-EPI equation(2009),CKD-EPI cystatin C(2012), CKD-EPI creatinine –cystatin C(2012). The cystatin C levels of serum and urine could be useful markers for renal dysfunction in type 2 diabetic patients with normoalbuminuria.
Conclusion; This finding has major implications for clinical research and early intervention to prevent development of chronic kidney disease in patients with type 2 Diabetes mellitus.
Keywords: Cystatin C, Diabetic Nephropathies, Albuminuria
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