TO FIND OUT THE COLONIZATION OF CLOSTRIDIUM DIFFICILE IN PATIENTS WITH MORE THAN 48 HOURS OF ADMISSION AND HAVING GASTROINTESTINAL SYMPTOMS

Authors

  • Sanjay Singh Demonstrator, Department of Microbiology, ABVGMC Vidisha, (M.P.)
  • Vaibhav Mishra Professor, Department of Microbiology, G.R. Medical college, Gwalior (M.P.)
  • Sweta Sahai Associate Professor, Department of Medicine, G.R. Medical college, Gwalior (M.P.)
  • Deepak Kumar Uikey Assistant Professor, Dept. of Paediatrics, Atal Bihari Vajpayee Government Medical College, Vidisha (M.P.)

DOI:

https://doi.org/10.32553/ijmbs.v5i5.1913

Keywords:

colonization, Clostridium difficile & gastrointestinal.

Abstract

Background & Method: Place of Study in Department of Microbiology, Gajra Raja Medical College, Gwalior Study was conducted on 600 patients admitted in various wards in G.R. Medical College, Gwalior and associated J A Group of Hospital Gwalior (MP).

Result: Among 600 suspected patients studied, maximum number, 287 (47.83%) belong to age group 19-49 years and minimum number 20 (3.33% belong to more than 75 years age group.

Male were more (58.83%) than female (41.16%) in studied suspected patients.

Fever was the most prevalent presenting symptom with 350 (58.33%) suspected patients. This was followed by abdominal pain 200 (33.33%) patients and diarrhoea in 118 (19.67%) suspected patients.

The least culture positivity was found in suspected patient who had admitted for 3-10 days (2.42 %). The maximum number of positive culture were found in patients with hospital stay more than 26 days which mean that duration of hospital stay correlate with positivity of culture.

  1. difficile was isolated in 5.71 % of the gastric acid suppressants using patients while its positivity in non gastric acid suppressants user was 2.72 %.

Conclusion: The prevalence of C. difficile in 600 hospitalized patients was found to be 5.17%.in our hospital. It was less as compare to other studied conducted earlier.   Cause of less prevalence may be due to various factors like the decreased use of Clindamycin  in our hospital. Secondly, antibiotics effective against C. difficile such as Metronidazole have been included as the first line drugs in suspected CDAD cases.

Colonization of C. difficile has been traditionally associated with hospitalization, advance age, underlying illness, gastric acid suppressant use and most prominently to use of antimicrobials. Uses of antibiotics, long stay in hospital and advance age was the most common risk factor in our study.

Keywords: colonization, Clostridium difficile & gastrointestinal.

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Published

2021-05-21

How to Cite

Singh, S. ., Mishra, V. ., Sahai, S. ., & Uikey, D. K. . (2021). TO FIND OUT THE COLONIZATION OF CLOSTRIDIUM DIFFICILE IN PATIENTS WITH MORE THAN 48 HOURS OF ADMISSION AND HAVING GASTROINTESTINAL SYMPTOMS. International Journal of Medical and Biomedical Studies, 5(5). https://doi.org/10.32553/ijmbs.v5i5.1913

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