ROLE OF D-DIMER AND SERUM LDH IN DETERMINING SEVERITY, PROGRESSION AND PROGNOSIS OF COVID -19 PATIENTS.

Abstract

Background: D- dimer and serum LDH is inflammatory marker which can be used to determine severity, progression and prognosis of covid 19.

Aim: To establish role of D-dimer and serum LDH in determining severity, progression and prognosis of covid 19 patients.

Result: The study population included 43 males and 32 females having COVID- 19 infection. The study showed that raised D-dimer levels were associated with increased coagulation activity and thereby poor prognosis. The study also showed that all the patients with raised serum LDH levels had more severe form of disease leading to rapid disease progression and prolonged hospital stay.

Conclusion: Any abnormal rise in D-dimer levels along with other inflammatory markers suggests that the patient requires vigorous anticoagulation therapy. The serum LDH’s elevated levels are usually employed in determining the disease progression from mild to moderate and severe forms.

Keyword: covid 19, D-dimer, serum LDH