PREVALENCE OF IRON DEFICIENCY ANEMIA AND ITS OUTCOME WITH THREE MONTHS ORAL IRON THERAPY IN PATIENTS WITH CHRONIC HEART FAILURE

Abstract

Background: To find out the prevalence of Iron deficiency Anemia in CHF patient. Prognostic outcome of treating the underlying  Iron deficiency anemia in CHF patient  with 3 month oral iron therapy will be measured by peak oxygen uptake, 6 minute walk test, 2D-Echo finding. Methods: The present study was conducted in Cardiac Care Unit (ICCU) of Medicine Department, Dr. S. N. Medical College, Jodhpur. Detailed data collected from 200 patients of congestive heart failure with reduced ejection fraction (LVEF<45%). Patients of acute decompensated heart failure were managed according to standard management guidelines and stabilized. After stabilizing the patient, they were investigated according to the patient Performa.

Results: Before therapy, 4 patients had NYHA class II symptoms (9.8%) and 13 had NYHA class III symptoms (31.7%). After 3 months of oral iron therapy, 6 patients were having NYHA class I symptoms, 13 having NYHA class II symptoms and 19 patients were having NYHA class 13 symptoms out of 41 patients. This shows significant improvement in NYHA functional class (P value<0.001). Functional status although improved without change in LV dimensions. Conclusion: Patient with chronic heart failure has high morbidity and mortality despite multimodal therapy. Iron deficiency anemia is common associated co morbidity in HF patients. Oral Iron therapy is associated with improvement in NYHA functional class, patient’s global assessment and 6MWT distance.

Keywords: NYHA, MWT, CHF