A CROSS SECTIONAL STUDY ON MEAN PLATELET VOLUME LEVEL IN CASES OF ACUTE MYOCARDIAL INFARCTION

Abstract

Previous data suggests that only 1/3^rd of patients presenting with chest pain to hospital requires hospitalisation and emergency care but in absence of segregation of these cases in the beginning physicians over admit such patients and it burns out precious resources and also reduces the quality of care for those who actually requires it. Platelet indices (MPV) is a simple economical tool which might be useful as an assisting rule out test in conjunction with other cardiac biomarkers in the early prediction of acute myocardial infarction in patients presenting with acute onset chest pain. The study was a hospital based observational cross sectional study conducted in which patients admitted with diagnosis of acute myocardial infarction during the span of study period were enrolled in the study after their written consent. Total 61 patients of acute MI were included in our study. All patients’ blood samples were taken on admission and Mean Platelet Volume was calculated. In our study the incidence of MI was found higher in males than in females. Prevalence of diabetes mellitus was found to be higher in males than in females as among 38 males 19 patients (50%) had history of DM as compared to only patients  had history of DM among total of 23 females. Patients presented with history of DM had higher values of MPV (mean 10.708) as compared to non DM patients (mean 10.43). Mean platelet values were found to be higher in males than the females. The study population MPV was also studied for correlation with the clinical presentation of patients. In all patients it was found that patients mean MPV values were lower in patients presented with chest pain , breathlessness , palpitation , pedal edema. But on performing t test the p values for chest pain, breathlessness, palpitation and pedal edema were 0.459, 0.749, 0.771 and 0.086 respectively. All were >0.05 and statistically non-significant. So although all symptoms had negative impact on MPV value the relation could not be established.

Keywords : Mean Platelet Volume Level ,  Acute Myocardial Infarction