A Study on the Lipid Profile of Hypertensive Patients

Abstract

Background: Dyslipidaemia and hypertension are the commonest risk factors for coronary artery disease (CAD). To study the lipid profile in hypertensive patients.

Methods: The present study was carried out on a total of 100 hypertensive patients attending our Hospital and 100 age and sex matched healthy controls. Twelve hour fasting lipid analysis was done for Serum triglycerides (TG), total cholesterol(TC), High Density Lipoprotein (HDL), Low Density Lipoprotein (LDL).

Results: The Mean serum total cholesterol values were highly significant in hypertensive subjects (235.36±32.36mg/dL) as compared to the healthy control subjects (152.36±12.01mg/dL). The mean serum TG level was 110.36±16.12 mg/dl in healthy control subjects, and 215.23±35.36 mg/dl in hypertensive patients. This difference was highly significant. The mean values for HDL was 27.23±6.02 mg/dL for hypertensive subjects whereas 43.21±5.36 mg/dl for healthy control subjects, respectively. The Mean serum LDL values were highly significant in hypertensive subjects (154.36±31.26 mg/dL) as compared to the healthy control subjects (95.36±16.02mg/dL).

Conclusion: All the lipid profile like cholesterol, LDL, TG and HDL were derange in the hypertensive than those in the healthy controls.

Keywords: Hypertension ,Lipid profile, HDL ,TG , LDL.