UNUSUAL PRESENTATION OF HAIRY CELL LEUKEMIA: A CASE REPORT

Authors

  • Dr. Vartika Sachdeva Junior Resident, Department of Pathology. Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
  • Dr. Mansi Kala Assistant Professor, Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
  • Dr. Sushil Kumar Shukla Senior Resident, Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
  • Dr. Anuradha Kusum Professor and Head, Department of Pathology, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, Uttarakhand, India
  • Dr. Kunal Das Assistant Professor, Department of Pediatrics, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University ,Dehradun, Uttarakhand, India

DOI:

https://doi.org/10.32553/ijmbs.v3i6.338

Keywords:

Hairy cell leukemia, Splenomegaly, Immunohistochemistry

Abstract

Hairy cell leukemia is a chronic B cell lymphoproliferative disorder,which is uncommon and constitutes around  two percent of  hematolymphoid malignancies. HCL commonly involves bone marrow and spleen and  rarely peripheral blood . Splenomegaly is  a prominent feature and  is seen in around 70 to 100% of  HCL cases as reported  in various case reports. Sometimes the absence of splenomegaly rules out the diagnosis of HCL and   is misdiagnosed as aplastic anemia. Thus the aim of our study is to understand the importance and keep a high level of suspicion in such cases. As in present case there was no evidence of splenomegaly clinically or radiology, but the morphologic features on biopsy had suggested HCL which was further confirmed on immunophenotyping. The purpose of this case report is to highlight the importance of the fact that HCL can present even without splenomegaly.

Keywords: Hairy cell leukemia, Splenomegaly, Immunohistochemistry

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Published

2019-06-25

How to Cite

Sachdeva, D. V., Kala, D. M., Shukla, D. S. K., Kusum, D. A., & Das, D. K. (2019). UNUSUAL PRESENTATION OF HAIRY CELL LEUKEMIA: A CASE REPORT. International Journal of Medical and Biomedical Studies, 3(6), 201–203. https://doi.org/10.32553/ijmbs.v3i6.338

Issue

Vol. 3 No. 6 (2019)

Section

Research Articles