A HOSPITAL BASED COMPARATIVE STUDY OF TOLERABILITY AND EFFICACY OF TRAMADOL VERSUS ACECLOFENAC ON PATIENTS WITH OSTEOARTHRITIS OF KNEE JOINT.

Authors

  • Dr. Sara Sultana Tutor, Department of Pharmacology, Jawahar Lal Nehru Medical College, Bhagalpur, Bihar, India.
  • Dr. Braj Nandan Kumar Sah Tutor, Department of Pharmacology, Jawahar Lal Nehru Medical College, Bhagalpur, Bihar, India.

DOI:

https://doi.org/10.32553/ijmbs.v3i8.490

Keywords:

Osteoarthritis of knee, WOMAC osteoarthritis index, Visual Analogue Scale

Abstract

Objectives: This present study was done to compare the tolerability and efficacy of tramadol versus aceclofenac in terms of WOMAC Osteoarthritis Index and Visual Analogue Scale of patients with osteoarthritis of knee joint.

Methods: A detail history, clinical examinations and relevant investigations were performed to all cases of osteoarthritis of knee joint. Group A patients were advised to receive tramadol 75 mg twice daily for 8 weeks, and group B patients were advised to receive aceclofenac 100 mg twice daily for 8 weeks. And we had evaluated the WOMAC Osteoarthritis Index and VAS score of first day and last day visit of patients with osteoarthritis of knee joint.

Results: Data was analyzed by using SPSS (version 26) software. Paired sample statistical methods were used. Mean and standard deviation was observed and mean differences were compared. P value was taken less than or equal to 0.05 (p?0.05) for significant differences.

Conclusions: This present study concluded that the WOMAC Osteoarthritis Index score and VAS score of patients who had received aceclofenac medication had statistically significant differences as well as greater mean differences than patients who received tramadol. Hence, aceclofenac is effective drugs than tramadol in terms of efficacy and tolerability of patients with osteoarthritis of knee joint.

Key words: Osteoarthritis of knee, WOMAC osteoarthritis index, Visual Analogue Scale.

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Published

2019-08-25

How to Cite

Sultana, D. S., & Sah, D. B. N. K. (2019). A HOSPITAL BASED COMPARATIVE STUDY OF TOLERABILITY AND EFFICACY OF TRAMADOL VERSUS ACECLOFENAC ON PATIENTS WITH OSTEOARTHRITIS OF KNEE JOINT. International Journal of Medical and Biomedical Studies, 3(8), 189-195. https://doi.org/10.32553/ijmbs.v3i8.490

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Section

Research Articles