COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF DICLOFENAC AND ETORICOXIB ON PATIENTS WITH INFLAMED KNEE JOINT

Authors

  • Amit Kumar Jha Associate Professor, Department of Pharmacology, Darbhanga Medical College and Hospital Laheriasarai, Darbhanga, Bihar, India
  • Raj Ranjan Prasad Professor and H.O.D. Department of Pharmacology, Darbhanga Medical College and Hospital Laheriasarai, Darbhanga, Bihar, India

DOI:

https://doi.org/10.32553/ijmbs.v4i3.1037

Keywords:

Etoricoxib, Diclofenac, Anti inflammatory effect

Abstract

Non steroidal anti-inflammatory drugs are non-narcotic or non opioid analgesics.Various exogenous and endogenous stimuli incite a complex reaction in vascularized connective tissue called inflammation. Preferential COX-2 inhibitors named diclofenac and Selective COX-2 inhibitor named etoricoxib was taken for my present work and anti inflammatory effect was compared with control and with each other. Student-t-test-was done to compare result. It was found that inflammation varied significantly across the three groups (P=.000) Compared to control, inflammation was less in both diclofenac and etoricoxib (P=.00). Reduction of inflammation with diclofenac was less, in comparison to etoricoxib at end. Etoricoxib is more efficacious than diclofenac.

Keywords: Etoricoxib, Diclofenac, Anti inflammatory effect.

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Published

2020-03-16

How to Cite

Jha, A. K., & Prasad, R. R. (2020). COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF DICLOFENAC AND ETORICOXIB ON PATIENTS WITH INFLAMED KNEE JOINT. International Journal of Medical and Biomedical Studies, 4(3). https://doi.org/10.32553/ijmbs.v4i3.1037

Issue

Vol. 4 No. 3 (2020)

Section

Articles