COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF ACECLOFENAC AND DICLOFENAC ON HUMAN BY CLINICAL TRIAL

Authors

  • Amit Kumar Jha Associate Professor, Department of Pharmacology, Darbhanga Medical College and Hospital, Laheriasarai, Darbhanga, Bihar

DOI:

https://doi.org/10.32553/ijmbs.v5i1.1652

Keywords:

Aceclofenac, diclofenac, Anti inflammatory effect

Abstract

Various exogenous and endogenous stimuli incite a complex reaction in vascularized connective tissue called inflammation. Non sterodial antiinflammatory drugs are used to reduce inflammation Preferential COX-2 inhibitors namely diclofenac and aceclofenac was taken for my present work and anti inflammatory effect was compared with control and with each other. Student-t-test-was done to compare result. It was found that inflammation varied significantly across the three groups (P=000) compared to control, in~lammation was less in both diclofenac and aceclofenac (P=00). Reduction of inflammation with diclofenac was less, in comparision to aceclofenac at end. Aceclofenac is more efficacious than diclofenac.

Keywords: Aceclofenac, diclofenac, Anti inflammatory effect

Downloads

Published

2021-01-16

How to Cite

Jha, A. K. . (2021). COMPARATIVE STUDY OF ANTI-INFLAMMATORY EFFECT OF ACECLOFENAC AND DICLOFENAC ON HUMAN BY CLINICAL TRIAL. International Journal of Medical and Biomedical Studies, 5(1). https://doi.org/10.32553/ijmbs.v5i1.1652

Issue

Section

Articles